Projects

Ongoing:

Investigation of the Presence of Desmin in the Nucleus of Human Skeletal Muscle Cells. 2020. TUBİTAK Project no. 120Z351. (PI: Ecem Kural Mangit)

Advisor 

Investigation of Potential Mechanisms for Nuclear Transport of Desmin. 2021. TUBİTAK, Project no.  120Z946.
The goal of this project is to investigate the potential nuclear import/export mechanisms of desmin  in skeletal muscle cells.

PI

Developing a High-performance Mechanical Loading Cell Stretching Device. 2021. TUBITAK Project no: 120E472.
Advisor
System identification of the dynamics of multi-Sensory integration. 2021. H2020 Project no: 101026643.
Advisor
Behavioral Mechanisms of Active Sensing. 2021. TUBITAK, Project no: 120E198
Advisor
Investigation of Ocular Growth Pathology by Generating LRP5 Mutant Zebrafish Via CRISPR / Cas9. 2021. TUBITAK Project no: 121S010.
Advisor
System identification of Multi-Sensory Integration in Zebrafishı. 2021. TUBITAK Project no: 120E054

Completed:

Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells. TUBITAK (The Scientific and Technological Research Council of Turkey), Project no: 116S307 (2017-2021).
The goal of this project was to elucidate the role of the nuclear envelope protein LAP1B in the regulation of gene expression in muscle cells.

PI

Development of CRISPR/Cas9 genome editing tools in zebrafish for rare diseases modeling. HÜBAP (Hacettepe University Scientific Research Projects), Project no: TAY-2017-12735 (2017-2020).
The goal of this project was to develop CRISPR/Cas9 genome editing tools in zebrafish in order to create different types of mutations (knockout and knockin) representing rare disorders.

PI

Xmu-Mp-1 Application to Desma Mutant Zebra Fish Model For Treatment. HÜBAP (Hacettepe University Scientific Research Projects), Project no: TYL-2018-17472 (2018-2021).

PI

Investigation of interaction partners of desmin and laminB using high resolution mass spectrometry. HUBAP, Project no: THD-2018-17210.
The goal of this project was to elucidate the interaction partners of desmin and lamin B in skeletal muscle tissue of zebrafish.

PI

Investigation of the effect of a desmin mutation on desmin protein function by using zebrafish model. TUBITAK, Project no: 214S174 (2015-2018).
The goal of this project was to model in zebrafish a limb-girdle muscular dystrophy phenotype caused by a mutation in the tail domain of desmin previously identified by our group.

PI

Investigation of a Novel Gene Responsible for Limb-Girdle Muscular Dystrophy. TUBITAK, Project no: 112S271 (2012-2015).

PI

Investigation of the inflammatory effect of AbetaPP induced ST6Gal1 secretion from myogenic cell line. TUBITAK, Project no: 111S320 (2011-2012).

Research Assistant